5/26/2025
Last update
5/26/2025
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.2
USERS' SCORE
Good
Based on 7 Reviews
8.1
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine HCl)
25 mg
1,471%
Top Medical Research Studies
7
We explored the relationship between vitamin B6 intake and the severity of symptoms in individuals with irritable bowel syndrome (IBS). Through a study involving 17 participants diagnosed with IBS according to the Rome II criteria, we gathered daily symptom reports and food intake logs over a week.
Our findings indicated that the only significant dietary component linked to symptom severity was vitamin B6. Participants generally consumed less than the recommended daily intake of vitamin B6, averaging just 0.9 mg per day, compared to the suggested amounts of 1.6 mg for men and 1.2 mg for women. Notably, a higher symptom score correlated with lower vitamin B6 consumption.
This suggests that individuals with IBS may benefit from increasing their vitamin B6 intake. Although this study has limitations—being small in scale and cross-sectional—it highlights a potential dietary factor that may impact the management of IBS symptoms.
Our findings indicated that the only significant dietary component linked to symptom severity was vitamin B6. Participants generally consumed less than the recommended daily intake of vitamin B6, averaging just 0.9 mg per day, compared to the suggested amounts of 1.6 mg for men and 1.2 mg for women. Notably, a higher symptom score correlated with lower vitamin B6 consumption.
This suggests that individuals with IBS may benefit from increasing their vitamin B6 intake. Although this study has limitations—being small in scale and cross-sectional—it highlights a potential dietary factor that may impact the management of IBS symptoms.
Read More
9.5
In our exploration of how vitamin B6 influences irritable bowel syndrome (IBS), we conducted a controlled, double-blind study involving 25 IBS patients who met the Rome IV criteria. These individuals were randomly assigned to receive either a novel formulation combining Bifidobacterium longum BB536, Lactobacillus rhamnosus HN001, and vitamin B6, or a placebo for one month before switching treatments.
We observed significant improvements in several IBS symptoms when patients were treated with the vitamin B6 probiotic combination compared to the placebo. Specifically, abdominal pain showed a notable decrease of nearly 49%, and bloating symptoms dropped by over 36%. Furthermore, the overall severity of the disease lessened substantially, suggesting that vitamin B6 in conjunction with these probiotics may play an essential role in managing IBS.
The trial also revealed improvements in intestinal permeability, which is a key factor in gut health. We noted an increase in beneficial gut bacteria, which indicates a revitalization of the intestinal microbiota during treatment. While the study's findings support the benefits of the B6 probiotic blend in alleviating IBS symptoms, it is important to recognize that these symptoms could be related to the probiotics themselves rather than the vitamin B6 alone.
We observed significant improvements in several IBS symptoms when patients were treated with the vitamin B6 probiotic combination compared to the placebo. Specifically, abdominal pain showed a notable decrease of nearly 49%, and bloating symptoms dropped by over 36%. Furthermore, the overall severity of the disease lessened substantially, suggesting that vitamin B6 in conjunction with these probiotics may play an essential role in managing IBS.
The trial also revealed improvements in intestinal permeability, which is a key factor in gut health. We noted an increase in beneficial gut bacteria, which indicates a revitalization of the intestinal microbiota during treatment. While the study's findings support the benefits of the B6 probiotic blend in alleviating IBS symptoms, it is important to recognize that these symptoms could be related to the probiotics themselves rather than the vitamin B6 alone.
Read More
8
We conducted a study to assess the effectiveness of a dry jelly concentrate containing vitamin B6, along with inulin and curcumin, on patients with irritable bowel syndrome (IBS) with constipation (IBS-C). Fifty patients who met the criteria for IBS-C were divided into two groups. One group received the jelly drinks alongside a standard diet for two weeks, while the control group followed the standard diet only.
Throughout the study, we carefully monitored changes in abdominal pain, bloating, stool frequency, and overall quality of life. The results showed that those who consumed the jelly concentrate experienced significant improvements in several gastrointestinal parameters. For instance, stool frequency increased, abdominal pain decreased, and there was a notable enhancement in quality of life ratings.
It's worth mentioning that while vitamin B6 was part of the jelly formulation, the specific benefits attributed solely to vitamin B6 are difficult to isolate. The improvements in the jelly group indicate that the combination of ingredients worked well together to alleviate symptoms of IBS-C. However, the control group did show some improvement in pain and bloating, which suggests that dietary factors alone can also play a role.
Overall, the inclusion of this jelly concentrate could be a beneficial addition for patients suffering from IBS-C, particularly due to its positive effects on stool parameters and quality of life. The study did not report any significant adverse effects, making this product a potentially safe option for those looking to manage their symptoms.
Throughout the study, we carefully monitored changes in abdominal pain, bloating, stool frequency, and overall quality of life. The results showed that those who consumed the jelly concentrate experienced significant improvements in several gastrointestinal parameters. For instance, stool frequency increased, abdominal pain decreased, and there was a notable enhancement in quality of life ratings.
It's worth mentioning that while vitamin B6 was part of the jelly formulation, the specific benefits attributed solely to vitamin B6 are difficult to isolate. The improvements in the jelly group indicate that the combination of ingredients worked well together to alleviate symptoms of IBS-C. However, the control group did show some improvement in pain and bloating, which suggests that dietary factors alone can also play a role.
Overall, the inclusion of this jelly concentrate could be a beneficial addition for patients suffering from IBS-C, particularly due to its positive effects on stool parameters and quality of life. The study did not report any significant adverse effects, making this product a potentially safe option for those looking to manage their symptoms.
Read More
Most Useful Reviews
10
Less stress
Despite my initial dislike of Solgar, these vitamins are brilliant! They are 100% effective. I've become calmer, less irritable, and the stress has passed, allowing me to stop worrying about trivial matters.
Read More
9
Condition improved
I became less irritable, my sleep normalised, and my overall condition improved. Excellent brand; I chose it without hesitation. I would appreciate it if you find this review helpful!
Read More
7.5
Calm and less irritable
12 people found this helpful
Good soothing. I advise. All irritability and anger have subsided. I began a 6-week course after my friend, a pharmacist, suggested it, stating that this preparation is more expensive in our chemists. The course was prompted by my irritability, anger, and psychosis. After two weeks, I began to notice a difference; I became calmer and less irritable. I took 25 mg as it was my first time using vitamin B6.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.2
- All Researches
9.5
In our exploration of how vitamin B6 influences irritable bowel syndrome (IBS), we conducted a controlled, double-blind study involving 25 IBS patients who met the Rome IV criteria. These individuals were randomly assigned to receive either a novel formulation combining Bifidobacterium longum BB536, Lactobacillus rhamnosus HN001, and vitamin B6, or a placebo for one month before switching treatments.
We observed significant improvements in several IBS symptoms when patients were treated with the vitamin B6 probiotic combination compared to the placebo. Specifically, abdominal pain showed a notable decrease of nearly 49%, and bloating symptoms dropped by over 36%. Furthermore, the overall severity of the disease lessened substantially, suggesting that vitamin B6 in conjunction with these probiotics may play an essential role in managing IBS.
The trial also revealed improvements in intestinal permeability, which is a key factor in gut health. We noted an increase in beneficial gut bacteria, which indicates a revitalization of the intestinal microbiota during treatment. While the study's findings support the benefits of the B6 probiotic blend in alleviating IBS symptoms, it is important to recognize that these symptoms could be related to the probiotics themselves rather than the vitamin B6 alone.
We observed significant improvements in several IBS symptoms when patients were treated with the vitamin B6 probiotic combination compared to the placebo. Specifically, abdominal pain showed a notable decrease of nearly 49%, and bloating symptoms dropped by over 36%. Furthermore, the overall severity of the disease lessened substantially, suggesting that vitamin B6 in conjunction with these probiotics may play an essential role in managing IBS.
The trial also revealed improvements in intestinal permeability, which is a key factor in gut health. We noted an increase in beneficial gut bacteria, which indicates a revitalization of the intestinal microbiota during treatment. While the study's findings support the benefits of the B6 probiotic blend in alleviating IBS symptoms, it is important to recognize that these symptoms could be related to the probiotics themselves rather than the vitamin B6 alone.
Read More
8
We conducted a study to assess the effectiveness of a dry jelly concentrate containing vitamin B6, along with inulin and curcumin, on patients with irritable bowel syndrome (IBS) with constipation (IBS-C). Fifty patients who met the criteria for IBS-C were divided into two groups. One group received the jelly drinks alongside a standard diet for two weeks, while the control group followed the standard diet only.
Throughout the study, we carefully monitored changes in abdominal pain, bloating, stool frequency, and overall quality of life. The results showed that those who consumed the jelly concentrate experienced significant improvements in several gastrointestinal parameters. For instance, stool frequency increased, abdominal pain decreased, and there was a notable enhancement in quality of life ratings.
It's worth mentioning that while vitamin B6 was part of the jelly formulation, the specific benefits attributed solely to vitamin B6 are difficult to isolate. The improvements in the jelly group indicate that the combination of ingredients worked well together to alleviate symptoms of IBS-C. However, the control group did show some improvement in pain and bloating, which suggests that dietary factors alone can also play a role.
Overall, the inclusion of this jelly concentrate could be a beneficial addition for patients suffering from IBS-C, particularly due to its positive effects on stool parameters and quality of life. The study did not report any significant adverse effects, making this product a potentially safe option for those looking to manage their symptoms.
Throughout the study, we carefully monitored changes in abdominal pain, bloating, stool frequency, and overall quality of life. The results showed that those who consumed the jelly concentrate experienced significant improvements in several gastrointestinal parameters. For instance, stool frequency increased, abdominal pain decreased, and there was a notable enhancement in quality of life ratings.
It's worth mentioning that while vitamin B6 was part of the jelly formulation, the specific benefits attributed solely to vitamin B6 are difficult to isolate. The improvements in the jelly group indicate that the combination of ingredients worked well together to alleviate symptoms of IBS-C. However, the control group did show some improvement in pain and bloating, which suggests that dietary factors alone can also play a role.
Overall, the inclusion of this jelly concentrate could be a beneficial addition for patients suffering from IBS-C, particularly due to its positive effects on stool parameters and quality of life. The study did not report any significant adverse effects, making this product a potentially safe option for those looking to manage their symptoms.
Read More
7
We explored the relationship between vitamin B6 intake and the severity of symptoms in individuals with irritable bowel syndrome (IBS). Through a study involving 17 participants diagnosed with IBS according to the Rome II criteria, we gathered daily symptom reports and food intake logs over a week.
Our findings indicated that the only significant dietary component linked to symptom severity was vitamin B6. Participants generally consumed less than the recommended daily intake of vitamin B6, averaging just 0.9 mg per day, compared to the suggested amounts of 1.6 mg for men and 1.2 mg for women. Notably, a higher symptom score correlated with lower vitamin B6 consumption.
This suggests that individuals with IBS may benefit from increasing their vitamin B6 intake. Although this study has limitations—being small in scale and cross-sectional—it highlights a potential dietary factor that may impact the management of IBS symptoms.
Our findings indicated that the only significant dietary component linked to symptom severity was vitamin B6. Participants generally consumed less than the recommended daily intake of vitamin B6, averaging just 0.9 mg per day, compared to the suggested amounts of 1.6 mg for men and 1.2 mg for women. Notably, a higher symptom score correlated with lower vitamin B6 consumption.
This suggests that individuals with IBS may benefit from increasing their vitamin B6 intake. Although this study has limitations—being small in scale and cross-sectional—it highlights a potential dietary factor that may impact the management of IBS symptoms.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
10
Less stress
Despite my initial dislike of Solgar, these vitamins are brilliant! They are 100% effective. I've become calmer, less irritable, and the stress has passed, allowing me to stop worrying about trivial matters.
Read More
9
Condition improved
I became less irritable, my sleep normalised, and my overall condition improved. Excellent brand; I chose it without hesitation. I would appreciate it if you find this review helpful!
Read More
7.5
Calm and less irritable
12 people found this helpful
Good soothing. I advise. All irritability and anger have subsided. I began a 6-week course after my friend, a pharmacist, suggested it, stating that this preparation is more expensive in our chemists. The course was prompted by my irritability, anger, and psychosis. After two weeks, I began to notice a difference; I became calmer and less irritable. I took 25 mg as it was my first time using vitamin B6.
Read More
7.5
Reduced irritability
7 people found this helpful
Soothes well; all irritability and anger have disappeared. My skin feels smooth and soft since starting vitamin B6. A friend advised me on the pharmacist, saying that this medicine is pricier in our pharmacies, while it is much cheaper here. I noticed a change after two weeks—I became calmer and less irritable.
Read More
6
Less irritable
2 people found this helpful
I take these vitamins during the second phase of my menstrual cycle, halving the dosage as it was too high. They are effective, and I’ve noticed I become slightly less irritable during this time.
Read More
Frequently Asked Questions
7.5
Calm and less irritable
12 people found this helpful
Good soothing. I advise. All irritability and anger have subsided. I began a 6-week course after my friend, a pharmacist, suggested it, stating that this preparation is more expensive in our chemists. The course was prompted by my irritability, anger, and psychosis. After two weeks, I began to notice a difference; I became calmer and less irritable. I took 25 mg as it was my first time using vitamin B6.
7.5
Reduced irritability
7 people found this helpful
Soothes well; all irritability and anger have disappeared. My skin feels smooth and soft since starting vitamin B6. A friend advised me on the pharmacist, saying that this medicine is pricier in our pharmacies, while it is much cheaper here. I noticed a change after two weeks—I became calmer and less irritable.
9
Condition improved
I became less irritable, my sleep normalised, and my overall condition improved. Excellent brand; I chose it without hesitation. I would appreciate it if you find this review helpful!
7.5
More cheerful
I bought this B6 for my husband, based on a cardiologist's recommendation, and began taking it too as I felt irritable and fatigued. I wanted a magnesium preparation that included B6, but I found that magnesium oxide is poorly absorbed. So, I purchased Magnesium Citrate from Solgar and B6 separately. After about two weeks, I noticed the benefits; I became calmer and more cheerful. For sleep issues, I suggest taking them in the evening. I recommend buying them.
7
Improved sleep
Good Vitamin! I took it with magnesium and became less irritable; my sleep also improved.
6
Less irritable
2 people found this helpful
I take these vitamins during the second phase of my menstrual cycle, halving the dosage as it was too high. They are effective, and I’ve noticed I become slightly less irritable during this time.
9.5
In our exploration of how vitamin B6 influences irritable bowel syndrome (IBS), we conducted a controlled, double-blind study involving 25 IBS patients who met the Rome IV criteria. These individuals were randomly assigned to receive either a novel formulation combining Bifidobacterium longum BB536, Lactobacillus rhamnosus HN001, and vitamin B6, or a placebo for one month before switching treatments.
We observed significant improvements in several IBS symptoms when patients were treated with the vitamin B6 probiotic combination compared to the placebo. Specifically, abdominal pain showed a notable decrease of nearly 49%, and bloating symptoms dropped by over 36%. Furthermore, the overall severity of the disease lessened substantially, suggesting that vitamin B6 in conjunction with these probiotics may play an essential role in managing IBS.
The trial also revealed improvements in intestinal permeability, which is a key factor in gut health. We noted an increase in beneficial gut bacteria, which indicates a revitalization of the intestinal microbiota during treatment. While the study's findings support the benefits of the B6 probiotic blend in alleviating IBS symptoms, it is important to recognize that these symptoms could be related to the probiotics themselves rather than the vitamin B6 alone.
We observed significant improvements in several IBS symptoms when patients were treated with the vitamin B6 probiotic combination compared to the placebo. Specifically, abdominal pain showed a notable decrease of nearly 49%, and bloating symptoms dropped by over 36%. Furthermore, the overall severity of the disease lessened substantially, suggesting that vitamin B6 in conjunction with these probiotics may play an essential role in managing IBS.
The trial also revealed improvements in intestinal permeability, which is a key factor in gut health. We noted an increase in beneficial gut bacteria, which indicates a revitalization of the intestinal microbiota during treatment. While the study's findings support the benefits of the B6 probiotic blend in alleviating IBS symptoms, it is important to recognize that these symptoms could be related to the probiotics themselves rather than the vitamin B6 alone.
8
We conducted a study to assess the effectiveness of a dry jelly concentrate containing vitamin B6, along with inulin and curcumin, on patients with irritable bowel syndrome (IBS) with constipation (IBS-C). Fifty patients who met the criteria for IBS-C were divided into two groups. One group received the jelly drinks alongside a standard diet for two weeks, while the control group followed the standard diet only.
Throughout the study, we carefully monitored changes in abdominal pain, bloating, stool frequency, and overall quality of life. The results showed that those who consumed the jelly concentrate experienced significant improvements in several gastrointestinal parameters. For instance, stool frequency increased, abdominal pain decreased, and there was a notable enhancement in quality of life ratings.
It's worth mentioning that while vitamin B6 was part of the jelly formulation, the specific benefits attributed solely to vitamin B6 are difficult to isolate. The improvements in the jelly group indicate that the combination of ingredients worked well together to alleviate symptoms of IBS-C. However, the control group did show some improvement in pain and bloating, which suggests that dietary factors alone can also play a role.
Overall, the inclusion of this jelly concentrate could be a beneficial addition for patients suffering from IBS-C, particularly due to its positive effects on stool parameters and quality of life. The study did not report any significant adverse effects, making this product a potentially safe option for those looking to manage their symptoms.
Throughout the study, we carefully monitored changes in abdominal pain, bloating, stool frequency, and overall quality of life. The results showed that those who consumed the jelly concentrate experienced significant improvements in several gastrointestinal parameters. For instance, stool frequency increased, abdominal pain decreased, and there was a notable enhancement in quality of life ratings.
It's worth mentioning that while vitamin B6 was part of the jelly formulation, the specific benefits attributed solely to vitamin B6 are difficult to isolate. The improvements in the jelly group indicate that the combination of ingredients worked well together to alleviate symptoms of IBS-C. However, the control group did show some improvement in pain and bloating, which suggests that dietary factors alone can also play a role.
Overall, the inclusion of this jelly concentrate could be a beneficial addition for patients suffering from IBS-C, particularly due to its positive effects on stool parameters and quality of life. The study did not report any significant adverse effects, making this product a potentially safe option for those looking to manage their symptoms.
7
We explored the relationship between vitamin B6 intake and the severity of symptoms in individuals with irritable bowel syndrome (IBS). Through a study involving 17 participants diagnosed with IBS according to the Rome II criteria, we gathered daily symptom reports and food intake logs over a week.
Our findings indicated that the only significant dietary component linked to symptom severity was vitamin B6. Participants generally consumed less than the recommended daily intake of vitamin B6, averaging just 0.9 mg per day, compared to the suggested amounts of 1.6 mg for men and 1.2 mg for women. Notably, a higher symptom score correlated with lower vitamin B6 consumption.
This suggests that individuals with IBS may benefit from increasing their vitamin B6 intake. Although this study has limitations—being small in scale and cross-sectional—it highlights a potential dietary factor that may impact the management of IBS symptoms.
Our findings indicated that the only significant dietary component linked to symptom severity was vitamin B6. Participants generally consumed less than the recommended daily intake of vitamin B6, averaging just 0.9 mg per day, compared to the suggested amounts of 1.6 mg for men and 1.2 mg for women. Notably, a higher symptom score correlated with lower vitamin B6 consumption.
This suggests that individuals with IBS may benefit from increasing their vitamin B6 intake. Although this study has limitations—being small in scale and cross-sectional—it highlights a potential dietary factor that may impact the management of IBS symptoms.
References
- Bonfrate L, Di Palo DM, Celano G, Albert A, Vitellio P, et al. Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50:e13201. 10.1111/eci.13201
- Pilipenko VI, Teplyuk DA, Shakhovskaya AK, Isakov VA, Vorobyova VM, et al. [Dry jelly concentrate with vitamins and dietary fiber in patients with IBS with constipation: a comparative controlled study]. Vopr Pitan. 2015;84:83.
- Ligaarden SC, Farup PG. Low intake of vitamin B6 is associated with irritable bowel syndrome symptoms. Nutr Res. 2011;31:356. 10.1016/j.nutres.2011.04.001
